Qualitative analysis of the acetogenins from Annona coriacea (Annonaceae) leaves by HPLC-Q-Orbitrap and their antibacterial potential against oral pathogens

AP Terezan, JGM Junqueira, VG Wakui… - Natural Product …, 2022 - Taylor & Francis
AP Terezan, JGM Junqueira, VG Wakui, L Kato, CMA Oliveira, CHG Martins, MB Santiago
Natural Product Research, 2022Taylor & Francis
Araticum is an edible and appreciable fruit of Annona coriacea, which is popularly known as
a traditional herb in the Brazilian cerrado. A phytochemical study from the leaves of A.
coriacea showed that HPLC-ESI-Q-Orbitrap® provided through PRM experiments (MS2) is
an efficient method for the fast and accurate analysis of a complex mixture of annonaceous
acetogenins, with the identification of sylvaticin and gigantetrocin-A type acetogenins for the
first time. In addition, the crude leaf extract and acetogenin-rich fractions were assayed …
Abstract
Araticum is an edible and appreciable fruit of Annona coriacea, which is popularly known as a traditional herb in the Brazilian cerrado. A phytochemical study from the leaves of A. coriacea showed that HPLC-ESI-Q-Orbitrap® provided through PRM experiments (MS2) is an efficient method for the fast and accurate analysis of a complex mixture of annonaceous acetogenins, with the identification of sylvaticin and gigantetrocin-A type acetogenins for the first time. In addition, the crude leaf extract and acetogenin-rich fractions were assayed against Streptococcus mutans, S. mitis, S. sanguinis and S. salivarius strains, which are usually related to oral infections.
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